Semaglutide - Frequently Asked Questions

Semaglutide is a medication that belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists. It was initially developed to treat type 2 diabetes, but it has also shown promising results in promoting weight loss.

Semaglutide helps with weight loss by acting on the brain's appetite control centers, reducing hunger, and increasing feelings of fullness. It slows down the emptying of the stomach, which can help in reducing calorie intake. Additionally, it may also have effects on the reward system in the brain, reducing cravings for food.

Yes, semaglutide has been approved by the U.S. Food and Drug Administration (FDA) as a treatment for chronic weight management in adults with a body mass index (BMI) of 30 or greater, or with a BMI of 27 or greater and at least one weight-related comorbidity (such as high blood pressure, type 2 diabetes, or high cholesterol).

Clinical trials have shown that semaglutide can lead to significant weight loss in individuals with obesity. In a study called the STEP trial, participants who took semaglutide along with lifestyle modifications lost on average around 15% of their body weight over a 68-week period, compared to those who received a placebo.

Semaglutide is administered as a once-weekly subcutaneous injection. The medication comes in a pre-filled pen, and the injection is typically given in the abdomen, thigh, or upper arm.

Like any medication, semaglutide may have side effects. The most common side effects reported in clinical trials include nausea, diarrhea, vomiting, constipation, and abdominal pain. These side effects are generally mild to moderate and tend to improve over time.

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Semaglutide is specifically approved for use in adults with obesity who meet certain criteria, as mentioned earlier. It is important to consult with a healthcare professional to determine if semaglutide is appropriate for you, considering your medical history, current medications, and individual needs.

Semaglutide has not been studied in pregnant or breastfeeding individuals, and its use during pregnancy or breastfeeding is not recommended. It is important to discuss any potential pregnancy or breastfeeding plans with a healthcare professional before starting semaglutide or any other weight loss medication.

Semaglutide has not been studied for weight loss in adolescents or children, and its use in this population is not approved. It is important to consult with a healthcare professional to explore appropriate weight management options for adolescents or children.

Semaglutide can be used as a long-term solution for weight loss. In clinical trials, the weight loss effects of semaglutide were sustained over a 68-week period. However, it is important to maintain a healthy lifestyle, including a balanced diet and regular physical activity, to maximize the benefits of semaglutide and to prevent weight regain.

The use of semaglutide in combination with other weight loss medications has not been extensively studied. It is important to consult with a healthcare professional to discuss the potential benefits and risks of combining semaglutide with other weight loss medications.

Semaglutide may interact with certain medications, so it is important to inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, and supplements. They can assess any potential interactions and adjust your treatment plan accordingly.

The amount of weight loss achieved with semaglutide can vary among individuals. In clinical trials, participants lost an average of around 15% of their body weight over a 68-week period. However, individual results may vary, and it is important to maintain realistic expectations.

Coverage for semaglutide for weight loss may vary depending on your insurance plan. It is recommended to contact your insurance provider to determine the coverage and potential out-of-pocket costs associated with semaglutide.

It is important to consult with a healthcare professional to discuss your specific weight loss goals, medical history, and the potential benefits and risks associated with semaglutide for weight loss.